Spontaneously occurring angiotoxic derivatives of cholesterol
1979
An in vitro study of angiotoxicity and artheriosclerosis due to oxidative contaminants in USP-grade cholesterol, and an in vitro study of specific angiotoxic agents in USP-grade cholesterol are reported. One conclusion is that pure cholesterol (either endogenously synthesized or chemically isolated pure cholesterol) is not atherogenic. When cholesterol mixes with spontaneoulsy produced toxic derivatives, it may be highly atherogenic. Foods containing cholesterol should be stored in well sealed containers and refrigerated or frozen. Antioxidants may also provide protection.
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