Biosynthesis of the Marine Antibiotic Pentabromopseudilin. 2. The Pyrrole Ring
2005
PESCHKE, Jörg D. | Hanefeld, Ulf | Laatsch, Hartmut
The biosynthesis of the potent marine antibiotic, pentabromopseudilin (1), was investigated. Feeding studies with Alteromonas luteoviolaceus were performed on a defined medium. D,L-[5-¹³C]proline was incorporated symmetrically, demonstrating that the pyrrole ring of pentabromopseudilin is derived from proline.
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