NPK1, a nonessential protein kinase gene in Saccharomyces cerevisiae with similarity to Aspergillus nidulans nimA

Schweitzer, B.; Philippsen, P.

NPK1, a nonessential protein kinase gene in Saccharomyces cerevisiae with similarity to Aspergillus nidulans nimA

1992

Schweitzer, B. | Philippsen, P.

A new protein kinase gene [called NPK1 (for nonessential protein kinase)] has been found on chromosome I of Saccharomyces cerevisiae between CDC15 and ADE1. The 435 amino acid/48 kDa gene product is very similar to known protein kinases. It is most closely related to the nimA protein of Aspergillus nidulans, displaying 45.9% identity and 63.5% similarity in the protein kinase domain. A 1.4 kb transcript of the NPK1 gene was detected. Disruption of the NPK1 gene impedes neither growth on glucose or a variety of other carbon sources, nor mating or sporulation.

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AGROVOC Keywords

amino acid sequences aspergillus nidulans aspergillus niger chromosome mapping dna enzymology gene expression gene location genetics messenger rna mutagenesis plasmids saccharomyces cerevisiae

Bibliographic information

Published in

MGG

Volume 234 Issue 1 Pagination 164 - 167 ISSN 0026-8925

Other Subjects

Protein kinases; Sequence homology; Nucleic acid; Fungal proteins; Chromosome deletion; Molecular sequence data; Saccharomyces cerevisiae proteins; Fungal; Structural genes; Transcription (genetics); Nucleotide sequences; Amino acid sequence; Molecular sequence data; Base sequence; Nonessential genes; Cell cycle proteins; Protein serine-threonine kinases

Language

English

Type

Text; Journal Article

In AGRIS since: 2024-02-28

Format: MODS

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