Importance of molecular typing in confirmation of the source of a national hepatitis A virus outbreak in Norway and the detection of a related cluster in Germany
2015
Guzman-Herrador, Bernardo R. | Panning, Marcus | Stene-Johansen, Kathrine | Borgen, Katrine | Einöder-Moreno, Margot | Huzly, Daniela | Jensvoll, Laila | Lange, Heidi | Maassen, Sigrid | Myking, Solveig | Myrmel, Mette | Neumann-Haefelin, Christoph | Nygård, Karin | Wenzel, Jürgen J. | Øye, Ann Kristin | Vold, Line
In March 2014, after an increase of notifications of domestically acquired hepatitis A virus infections, an outbreak investigation was launched in Norway. Sequenced-based typing results showed that these cases were associated with a strain that was identical to one causing an ongoing multinational outbreak in Europe linked to frozen mixed berries. Thirty-three confirmed cases with the outbreak strain were notified in Norway from November 2013 to June 2014. Epidemiological evidence and trace-back investigations linked the outbreak to the consumption of a berry mix cake. Identification of the hepatitis A virus outbreak strain in berries from one of the implicated cakes confirmed the cake to be the source. Subsequently, a cluster in Germany linked to the cake was also identified.
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