A protein with several possible membrane-spanning domains encoded by the Drosophila segment polarity gene patched
1989
Nakano, Y. | Guerrero, I. | Hidalgo, A. | Taylor, A. | Whittle, J.R.S. | Ingham, P.W.
The patterning of cells in insect segments requires the exchange of information between cells, which in Drosophila depends on the activity of members of the segment-polarity class of genes. Here we report the molecular characterization of one such gene, patched. We find that patched encodes a large protein with several possible membrane-spanning domains and is expressed in a complex pattern during embryogenesis.
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