Effect of Picroliv on Rifampicin‐Induced Biochemical Changes in the Rat Liver and Serum
1996
Rastogi, Ravi | Saksena, Seema | Garg, Narendra Kumar | Dhawan, B. N.
Rifampicin was administered to rats (50 mg/kg, i.p. daily) for 2, 6, 12 or 24 days and selected biochemical parameters in liver and serum were measured 24 h after the last injection. Concomitant administration of picroliv (12 mg/kg) showed maximum hepatoprotective activity in the 6 day schedule. Administration of picroliv during the recovery phase in 12 and 24 day schedule expedited recovery of most parameters.
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