Synthesis of 1,2,4-triazine derivatives via [4 + 2] domino annulation reactions in one pot
2016
Tang, Dong | Wang, Jing | Wu, Ping | Guo, Xin | Li, Ji-Hui | Yang, Sen | Chen, Bao-Hua
Simple and efficient [4 + 2] domino annulation reactions have been developed for the synthesis of 1,2,4-triazine derivatives. The strategies exhibit high performance with moderate to high yields, using easily available materials including ketones, aldehydes, alkynes, secondary alcohols and alkenes, representing a powerful tool for the formation of potentially biologically active derivatives.
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