Different behaviors of benznidazole as free radical generator with mammalian and Trypanosoma cruzi microsomal preparations

Moreno, S.N.J.; Docampo, R.; Mason, R.P.; Leon, W.; Stoppani, A.O.M.

Different behaviors of benznidazole as free radical generator with mammalian and Trypanosoma cruzi microsomal preparations

1982

Moreno, S.N.J. | Docampo, R. | Mason, R.P. | Leon, W. | Stoppani, A.O.M.

Trypanosoma cruzi, different behaviors of benznidazole as free radical generator with mammalian and parasite microsomal preparations, different mechanism of benznidazole toxicity in T. cruzi and the mammalian host is postulated

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AGROVOC Keywords

animals drugs electron spin resonance spectroscopy free radicals hydrogen peroxide kinetics liver mechanism of action metabolism microsomes mitochondria nitroimidazoles rats rats toxicity trypanosoma cruzi

Bibliographic information

Published in

Archives of biochemistry and biophysics

Volume 218 Issue 2 Pagination 585 - 591 ISSN 0003-9861

Other Subjects

Species specificity; Trypanocidal agents; Inbred strains; Superoxides; Male

Language

English

Type

Journal Article; Text

In AGRIS since: 2024-02-28

Format: MODS

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Different behaviors of benznidazole as free radical generator with mammalian and Trypanosoma cruzi microsomal preparations

1982

AGROVOC Keywords

Bibliographic information