Ergosterols from Ganoderma sinense and their anti-inflammatory activities by inhibiting NO production
2019
Mei, Ren-Qiang | Zuo, Feng-Jiao | Duan, Xiao-Yan | Wang, Yi-Na | Li, Jun-Rong | Qian, Cheng-Zhen | Xiao, Ji-Ping
Three new ergosterols, ganocalidophins A–C (1‒3), along with four known ones, were isolated from the fruiting bodies of Ganoderma sinense. Their structures were established on the basis of extensive NMR and MS technologies, as well as the single crystal X-ray diffraction. Compounds 1‒3 and 6 exhibited inhibitory activities against NO production with IC50 of 17.7–32.4 μM.
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