Four new phenolic constituents from the rhizomes of Gastrodia elata Blume

Wang, Zhi-Wei; Li, Yun; Liu, Da-Hui; Mu, Yan; Dong, Hong-Jing; Zhou, Hong-Lei; Guo, Lan-Ping; Wang, Xiao

Four new phenolic constituents from the rhizomes of Gastrodia elata Blume

2019

Four new gastrodin derivatives containing a trans-cinnamoyl unit (1–4) and nine known compounds (5–13) were isolated from the rhizomes of Gastrodia elata Blume. All these compounds were evaluated for their neuroprotective effects against 6-hydroxydopamine-induced cell death, and compounds 7 and 12 showed potent activities with EC₅₀ values of 10.5 and 10.2 μM, respectively.

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AGROVOC Keywords

cell death phenolic compounds rhizomes

Bibliographic information

Published in

Natural product research

Volume 33 Issue 8 Pagination 1140 - 1146 ISSN 1478-6427

Publisher

Taylor & Francis

Other Subjects

Gastrodia elata; Neuroprotective effect; Median effective concentration; Neuroprotective effects; Grossamide; Phenolics; Gastrodia elata blume; N6-(4-hydroxybenzyl) adenosine

Language

English

Type

Text; Journal Article

In AGRIS since: 2024-02-28

Format: MODS

Data Provider

This bibliographic record has been provided by National Agricultural Library

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Links

DOI http://dx.doi.org/10.1080/14786419.2018.1460836

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