Inhibition of adherence and cytotoxicity by circulating immune complexes formed in experimental filariasis
1982
Karavodin, L.M. | Ash, L.R.
Brugia pahangi, circulating immune complexes from sera of chronically infected Meriones unguiculatus can block both adherence of peritoneal exudate cells to microfilariae and their subsequent cytotoxic destruction, adherence and cytotoxicity took place only in presence of specific antimicrofilarial sera, these reactions were enhanced by but not dependent on complement, macrophages were predominant adherent cell type, possible role of immune complexes in persistence of microfilaraemia in the jird
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