The synthesis of 3-amino-5-arylisothiazoles from propynenitriles
2018
Barton, Peter
A new synthesis of 3-amino-5-arylisothiazoles is reported. The reaction is operationally simple, utilises readily synthesised propynenitriles as starting materials and is tolerant of a range of functional groups. The optimised reaction conditions can also be used with 3-chloropropenenitriles in place of propynenitriles.
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