Selenium status in term infants fed human milk or infant formula with or without added selenium
1989
Litov, R.E. | Sickles, V.S. | Chan, G.M. | Hargett, I.R. | Cordano, A.
Selenium (Se) is an essential element for human nutrition. To date, infant formulas manufactured in the United States are not fortified with Se, but provide Se as an intrinsic part of the ingredients. Two studies were conducted to assess the plasma and RBC levels of Se and glutathione peroxidase activity (GSH-Px) in term infants. In Study 1, infants were fed either human milk, 0.29 micromole Se/L (23 micrograms Se/L), or one of two whey-predominant formulas containing only intrinsic Se, 0.16 micromole Se/L (13 micrograms Se/L), or intrinsic Se plus sodium selenite, with a total of 0.43 micromole Se/L (34 micrograms Se/L), from birth to 2 months of age. In Study 2, infants were fed either human milk, 0.32 micromole Se/L (25 micrograms Se/L), or one of two soy-based formulas containing only intrinsic Se, 0.19 micromole Se/L (15 micrograms Se/L), or intrinsic Se plus sodium selenite, with a total of 0.24 micromole Se/L (19 micrograms Se/L), from birth to 6 months of age. The results of the two studies showed that in infants with adequate selenium status at birth, whey-predominant formulas with or without added Se containing at least 0.16 micromole Se/L (13 micrograms Se/L) and soy-based formulas with or without added Se containing at least 0.19 micromole Se/L (15 micrograms Se/L) maintained Se status comparable to that observed in human milk fed infants.
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