Use of Bordetella bronchiseptica and Bordetella pertussis as live vaccines and vectors for heterologous antigens

Stevenson, A.; Roberts, M.

Use of Bordetella bronchiseptica and Bordetella pertussis as live vaccines and vectors for heterologous antigens

2003

Stevenson, A. | Roberts, M.

Bordetella pertussis and Bordetella bronchiseptica are respiratory pathogens of humans and animals respectively. Unlike many bacteria, they are able to efficiently colonise healthy ciliated respiratory mucosa. This characteristic of Bordetella spp. can potentially be exploited to develop efficient live vaccines and vectors for delivery of heterologous antigens to the respiratory tract. Here we review the progress in this area.

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AGROVOC Keywords

live vaccines

Bibliographic information

Published in

FEMS immunology and medical microbiology

Volume 37 Issue 2 Pagination 121 - 128 ISSN 0928-8244

Other Subjects

Mucosally-delivered vaccines; Vaccine vectors; Animal pathogenic bacteria; Attenuated live vaccines

Language

English

Note

In the thematic issue: new approaches to bacterial vaccine development/ edited by b.u. von specht.

Type

Journal Article; Text

In AGRIS since: 2024-02-28

Format: MODS

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Use of Bordetella bronchiseptica and Bordetella pertussis as live vaccines and vectors for heterologous antigens

2003

AGROVOC Keywords

Bibliographic information