Microbial transformation of prenylflavonoids from Psoralea corylifolia by using Cunninghamella blakesleeana and C. elegans
2015
Ma, Shunan | Zheng, Cheng | Feng, Li | Huang, Youwu | Wang, Rui | Huang, Cheng | Li, Yiming | Guo, Fujiang
Cunninghamella blakesleeana AS 3.0970 and AS 3.0910 and C. elegans AS 3.2028 were first used for biotransforming three major prenylflavonoids from Psoralea corylifolia, namely bavachinin, bavachin, and isobavachalcone. A total of seven biotransformation products, including six new compounds, were obtained and identified. The agonistic activities of peroxisome proliferator-activated receptor-γ against substrates and biotransformation products were also evaluated.
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