Antiviral Activity of Fattiviracin FV-8 against Human Immunodeficiency Virus Type 1 (HIV-1)
2001
HABIB, El-Sayed E. | YOKOMIZO, Kazumi | NAGAO, Kazuhiko | HARADA, Shinji | UYEDA, Masaru
A novel antiviral agent, fattiviracin FV-8, purified from the culture broth of Streptomyces microflavus strain No. 2445, showed potent antiviral activities against human immunodeficiency virus type 1 (HIV-1), herpes simplex virus type 1 (HSV-1), varicella-zoster virus (VZV), and influenza A and B viruses. The action mechanism of fattiviracin FV-8 against HIV-1 was examined. As a result, the agent was thought to act on HIV-1 particles directly without lysis of the particles, and it affords the inhibition of viral entry into the host cells.
Show more [+] Less [-]AGROVOC Keywords
Bibliographic information
This bibliographic record has been provided by National Agricultural Library
