Two new phenolic glucosides from marine-derived fungus Aspergillus sp
2022
Wen, Huiling | Zang, Yi | Zhu, Qianheng | Ouyang, Sheng | Luo, Juanjuan | Luo, Nianhua | Zhu, Hucheng | Zhang, Yonghui
Two new phenolic glucosides, including a new O-glycoside (1) and a new C-glycoside (2), were isolated from a marine-derived fungus Aspergillus sp. The structures of new compounds were elucidated through interpretations of spectroscopic evidence and high-resolution electrospray ionization mass spectrometry. The hexose unit of 1 was identified as β-D-glucose by comparison with an authentic sample via HPLC after acid hydrolysis and derivatization. All compounds were evaluated for their ability to inhibit LPS-induced NO production in RAW264.7 macrophages, but none of them displayed significant activity.
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