Efecto de la Amitriptilina en la Longitud y Peso de Larvas de Lucilia sericata Meigen1 | Amitriptyline Effect on Length and Weight of Lucilia sericata Meigen Larvae1
2018
Moreno-Guzmán, Cecilia Carolina | Rodriguez-Castro, Violeta Ariadna | Quiroz-Martinez, Humberto
Some drugs and their metabolites can affect the larval development of necrophagous insects, and may interfere the post-mortem interval estimation. The objective of this study was to evaluate the effect of amitriptyline on length and weight of Lucilia sericata larvae. Bottle traps with cattle liver were used to collect egg masses, which later were separated in two parts and placed in 1) liver paste with and 2) without amitriptyline. Each 8 hours, 10 larvae were removed to record their length and weight. Larvae of L. sericata with no amitriptyline consumption demonstrated greater length and weight compared to the group feeding on treated cattle liver. The last ones reached the third instar and the maximum size faster than the control group. Given that amitriptyline affects the length and weight of L. sericata larvae, presence of this substance in corpses shall be considered in the post-mortem interval estimation, the cause of death, and in the reconstruction of events surrounding the incident.
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