A novel nucleic acid aptamer tag: a rapid fluorescence strategy using a self-constructing G-quadruplex from AGG trinucleotide repeats
2018
Fu, Boshi | Park, Yoojin | Kim, Ki Tae | Chen, Kun | Zou, Guangrong | Wei, Qi | Peng, Shuang | Chen, Yuqi | Kim, Byeang Hyean | Zhou, Xiang
Herein, we have developed a novel fluorescence labeling strategy for nucleic acid aptamers based on self-assembling between AGG tri-nucleotide repeats and a pyrene-modified oligonucleotide. This strategy could be an effective tool for developing targeting–imaging systems and biosensor systems to detect target molecules.
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