Starch chemistry affects kinetics of glucose absorption and insulin response in swine
2010
Regmi, P.R. | Matte, J.J. | van Kempen, T.A.T.G. | Zijlstra, R.T.
Starch chemistry may affect kinetics of nutrient absorption and insulin secretion. The objective was to define the glucose absorption kinetics and insulin response in swine to diets containing starch with a wide range in chemistry and in vitro digestion patterns. Diets tested contained purified starch (700g/kg diet) ranging from rapid to slow digestible starch [maximal rate of in vitro glucose release (%)/min: 1.53, rapid; 0.94, moderate rapid; 0.37, moderate slow; and 0.14, slow]. In vitro rate of starch digestion was characterized using an assay modified after . In vivo kinetics were determined using four pigs (35.0±0.2kg) surgically fitted with catheters in the portal vein and carotid artery and a portal blood flow probe. Pigs were fed for 7-d periods in a 4×4 Latin square. On d 7, blood was collected for 12h postprandially. Net glucose absorption differed (P <0.05) among diets at 45, 90, 120, and 150min postprandial. Cumulative glucose absorption up to 12h did not differ among rapid, moderate rapid, and moderate slow digestible starch diets, but these diets had a higher (P <0.05) cumulative glucose absorption than slow digestible starch diets. In addition, portal plasma insulin and C-peptide release peaked at 30min postprandial and differed (P <0.05) among diets at 30 and 60min postprandial, except between moderate rapid and moderate slow digestible starch diets. In conclusion, starches with a wide difference in in vitro starch digestion affect kinetics of glucose absorption and insulin response in swine.
Show more [+] Less [-]AGROVOC Keywords
Bibliographic information
This bibliographic record has been provided by National Agricultural Library
