Elucidating the influence of environmentally relevant toxic metal mixture on molecular mechanisms involved in the development of neurodegenerative diseases: In silico toxicogenomic data-mining

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Publisher

Elsevier Inc.

Other Subjects

Ace; Superoxide dismutase 1; Solute carrier family 2 member 14; Eph receptor a1; Vegfa; Vitamin metabolism; Endothelin 1; Genome wide association study; Discoidin domain receptor tyrosine kinase 1; Peroxisome proliferator activated receptor gamma; Pheochromocytoma cell line; Paramyosin; Dipeptidyl peptidase like 6; Methylmercury compounds; Age-rage; Ataxin 2; Fus rna binding protein; Toxicogenomic data-mining; Myeloperoxidase; Dopamine receptor d2; Microrna 375; The comparative toxicogenomics database; Ribosomal protein l14; Copper transporter 1b; Ribosomal protein l23a; Nuclear factor erythroid 2-related factor 2; Heat shock protein; Nicotinamide adenine dinucleotide; High mobility group box 1; Hepatocyte growth factor; Carcinoembryonic antigen related cell adhesion molecule 6; Neurons; Bone marrow stromal cell antigen 1; Cystatin c; Solute carrier family 30 member 6; Microtubule associated protein tau; Alzheimer's disease; Wwox; Sequestosome 1; Dynamin 1 like; Mitogen-activated protein kinase kinasekinase 5; Growth factor independent protein 1; Monoamine oxidase b; Alzheimer disease; Adamts1; Peptide yy; Adam10; Enolase 1; Cd2 associated protein; Nitric oxide synthase 1; Solute carrier family 30 member 4; Heat shock protein family a (hsp70) member 9; Insulin like growth factor 1; Amyloid beta precursor protein; Aβ; Glutathione peroxidase 1; Prostaglandin-endoperoxide synthase 2; Vsnl1; Fibrinogen beta chain; Insulin like growth factor 2; Neurodegenerative diseases; Bridging integrator 1; Tnfrsf21; Solute carrier family 1 member 2; Beta-secretase 1; Autocrine motility factor receptor; Cytochrome p450 family 46 subfamily a member 1; Interleukin 1 beta; Parkin rbr e3 ubiquitin protein ligase; Transcription factor a; Nerve growth factor; Tar dna binding protein; Tp53; Non-smc condensin ii complex subunit g2; Nad (p)h quinone dehydrogenase 1; Solute carrier family 18 member a2; Parkinson's disease; Parkinson disease; Heme oxygenase 1; N-methyl-d-aspartate receptor; Glutathione s-transferase mu 1; Methylmercury; Neurodegeneration; Cyclic guanosine monophosphate; Heat shock protein family a (hsp70) member 1a; Tg; Advanced glycation end products' receptor; Insulin like growth factor 1 receptor; Ribosomal protein l6; Butyrylcholinesterase; Fc fragment of ige receptor ii; Microtubule associated protein 2; Microrna 146a; Bcl2 associated x apoptosis regulator; Prion protein; Glutathione s-transferase pi 1; Insulin like growth factor 2 receptor; Atpase cation transporting 13a2; Interleukin 13; Leucine rich repeat kinase 2; Abcb1; Coagulation factor ii; Thrombin; Toxicogenomics; Class ii; Dr alpha; Contactin associated protein 2; Fructose-bisphosphatase 1; Enolase 2; Brain derived neurotrophic factor; Dopa decarboxylase; Protein kinase g; S100 calcium-binding protein b; Apolipoprotein e; Cd40 ligand; Pten induced kinase 1; Paraoxonase 1; Tpp1; Trpm2; Reactive nitrogen species; Atp synthase f1 subunit alpha; Methylenetetrahydrofolate reductase; No observed adverse effect levels; Presenilin 1; Caspase 3; Corticotropin releasing hormone; Tmem230; Estrogen receptor 1; A2m; Cyclin g associated kinase; Transaldolase 1; Cyclic adenine monophosphate responsive element binding protein; Interleukin 6; Calmodulin 1; Tnfr1; Superoxide dismutase 2; Glycogen synthase kinase 3 beta; Pparg coactivator 1 alpha; Neuropeptide y; Tpi1; Synuclein alpha; Potassium inwardly rectifying channel subfamily j member 4; Gene ontology; Multiple sclerosis; Insulin receptor; Cytochrome p450 family 2 subfamily e member 1; Solute carrier family 6 member 3; Parkinsonism associated deglycase; Non-monotonic dose-response; Computer simulation; Phospholipase a2 group iva; Methylmercury; Ache; Experimental autoimmune encephalomyelitis; Optineurin; Solute carrier family 6 member 1; Interleukin 4; Glutathione-disulfide reductase; Tnf; Monoamine oxidase a; Tomm40; Bcl2 apoptosis regulator; Tnfr2; Vps35; Odorant-binding protein 99b; Glial fibrillary acidic protein; Clusterin; Ribosomal protein s8; Progesterone receptor membrane component 1; Glutathione s-transferase alpha 4; Glial cell derived neurotrophic factor; Th; Homeostatic iron regulator; Nitric oxide synthase 3; Class ii; Dr beta 5; Metastasis associated 1; Amyotrophic lateral sclerosis

Language

English

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Type

Journal Article; Text