Organocatalytic synthesis of amides from nitriles via the Ritter reaction
2011
Khaksar, Samad | Fattahi, Eskandar | Fattahi, Esmail
A simple, inexpensive, environmentally friendly, and efficient route for the synthesis of a wide variety of amides in high yields via the Ritter reaction of alcohols with nitriles has been demonstrated. Pentafluorophenyl ammonium triflate (PFPAT) is used as an organocatalyst and is air-stable, cost-effective, easy to handle, and easily removed from the reaction mixtures.
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