Pentasaccharide resin glycosides from Ipomoea cairica and their cytotoxic activities
2013
Yu, Bangwei | Luo, Jianguang | Wang, Junsong | Zhang, Dongming | Yu, Shishan | Kong, Lingyi
Six partially acylated pentasaccharide resin glycosides, cairicosides A–F, were isolated from the aerial parts of Ipomoea cairica. These compounds were characterized as a group of macrolactones of simonic acid A, partially acylated with different organic acids. The lactonization site of 11S-hydroxyhexadecanoic acid (jalapinolic acid) was bound to the second saccharide moiety at C-3 in cairicosides A–E, while at C-2 in cairicoside F. Structures were established by spectroscopic and chemical methods. Compounds cairicosides A–E exhibited moderate cytotoxicity against a small panel of human tumor cell lines with IC50 values in the range of 4.28–14.31μM.
Show more [+] Less [-]AGROVOC Keywords
Bibliographic information
This bibliographic record has been provided by National Agricultural Library