Synthesis of α,γ-Peptide Hybrids by Selective Conversion of Glutamic Acid Units
2012
Saavedra, Carlos J. | Boto, Alicia | Hernández, Rosendo
The site-selective modification of small peptides at a glutamate residue allows the ready preparation of α,γ-hybrids. In this way, a single peptide can be transformed into a variety of hybrid derivatives. The process takes place under very mild conditions, and good global yields are obtained.
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