Conformational control of HCl co-transporter: imidazole functionalised isophthalamide vs. 2,6-dicarboxamidopyridine
2007
Gale, Philip A. | Garric, Joachim | Light, Mark E. | McNally, Beth A. | Smith, Bradley D.
Replacement of the central isophthalamide core in a synthetic HCl receptor, with a 2,6-dicarboxamidopyridine, leads to a more preorganised molecular structure that exhibits higher chloride affinity and membrane transport flux.
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