Intermolecular Carboamination of Unactivated Alkenes
2018
Zhang, Yu | Liu, Haidong | Tang, Luning | Tang, Hai-Jun | Wang, Lu | Zhu, Chuan | Feng, Chao
Herein, we report the first example of group transfer radical addition of O-vinylhydroxylamine derivatives onto unactivated alkenes. By utilizing O-vinylhydroxylamine derivatives as both the N- and C-donors, this reaction enables intermolecular carboamination of unactivated alkenes in an atom economical fashion. As the process is initiated through N-radical addition followed by C-transfer, linear carboamination products are afforded. This differs from canonical radical carbofunctionalization of olefins, which typically favors branched product owing to initiation by C-radical addition.
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