Water-Based Black Phosphorus Hybrid Nanosheets as a Moldable Platform for Wound Healing Applications
2018
Huang, Xiao-Wei | Wei, Jing-Jing | Zhang, Meng-Ya | Zhang, Xue-Liang | Yin, Xiao-Fei | Lü, Junhua | Song, Ji-Bin | Bai, Shu-Meng | Yang, Huang-Hao
Black phosphorus (BP) nanosheets with unique biocompatibility and superior optical performance have attracted enormous attention in material science. However, their instability and poor solution-processability severely limit their clinical applications. In this work, we demonstrate the use of silk fibroin (SF) as an exfoliating agent to produce thin-layer BP nanosheets with long-term stability and facile solution-processability. Presence of SF prevents rapid oxidation and degradation of the resultant BP nanosheets, enhancing their performance in physiological environment. The SF-modified BP nanosheets exhibit subtle solution-processability and are fabricated into various BP-based material formats. As superior photothermal agents, BP-based wound dressings effectively prevent bacterial infection and promote wound repair. Therefore, this work opens new avenues for unlocking current challenges of BP nanosheet applications for practical biomedical purposes.
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