Synthesis of the Cancer-Associated KH-1 Antigen by Block Assembly of Its Backbone Structure Followed by One-Step Grafting of Three Fucose Residues
2017
Li, Qingjiang | Guo, Zhongwu
A robust, convergent, and efficient strategy was developed for the synthesis of the nonasaccharide cancer antigen KH-1. This strategy featured a one-pot block assembly of the linear hexasaccharide backbone using three disaccharides followed by grafting of three fucose residues onto the backbone in one step.
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