Myxococcus xanthus CbpC and CbpD containing two cAMP-binding domains are involved in temperature tolerance
2009
Ishibashi, K.(Kagawa Univ., Miki (Japan). Faculty of Agriculture) | Kimura, Y.
Myxococcus xanthus CbpC and CbpD contained two cAMP-binding domains that have partial primary structural similarity to cAMP-dependent protein kinase (PKA) regulatory subunits. cbpC and cbpD mutants, generated by gene disruption, showed normal growth, fruiting body formation, spore formation, and spore germination. However, cbpC and cbpD mutants cultured under high-temperature conditions exhibited a marked reduction in growth. In contrast to M. xanthus cbpB mutant, cbpC and cbpD mutant cells were not shown to sensitive to osmotic stress.
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