The use of monoclonal antibodies for purification of trichinella diagnostic antigens
1991
Lipatova, L.N.
Monoclonal antibodies obtained from spleen cells of mice immunized with somatic antigen of Trichinella larvae (2nd protein fraction) interacted with antigenic determinants of Trichinella larvae proteins with molecular mass 50-55 and 37-43 kd. Antigens with molecular mass 50-55 kd were separated by the method of affine chromatography with the use of monoclonal antibidies. The obtained proteins can be considered alternative antigens for use in immunodiagnostics of trichinellosis by the method of immunoferment analysis
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