Characteristic of high pathogenic avian influenza virus subtype H5N1 isolated from common gull (Larus canus) | Характеристика высокопатогенного штамма вируса гриппа H5N1-субтипа, выделенного от сизой чайки (Larus canus)
2010
Sharshov, K.A. | Kurskaya, O.G. | Zajkovskaya, A.V. | Susloparov, I.M. | Ternovoj, V.A. | Durymanov, A.G. | Zolotykh, S.L | Shestopalov, A.M. | Drozdov, I.G., State Research Center of Virology and Biotechnology, Novosibirsk Region (Russian Federation) | Yurlov, A.K., Russian Academy of Sciences. Siberian Branch, Novosibirsk (Russian Federation). Novosibirsk Science Center. Institute of Systematics and Animal Ecology
The study was aimed at biological characteristics of H5N1 influenza virus isolated from common gull on south of West Siberia in 2006. Isolation and characterization of biological characteristics performed according to recommendations of World Health Organization. Results showed that influenza virus A H5N1 was first isolated from common gull (Larus canus) in Russia. Antigen of isolated virus had significant affinity to polyclonal sera obtained against high pathogenic avian influenza viruses H5N1 circulating in South-East Asia. Phylogenetic analysis of isolated strain revealed its belonging to group of Qinghai-related variants of H5N1 influenza virus. Amino acid structure of hemagglutinin proteolytic cleavage site is characteristic for type A high pathogenicity avian influenza viruses. Experimental infection of chickens demonstrated high pathogenicity of the isolated virus. It is concluded that involvement of common gulls in circulation of subtype H5N1 influenza virus is demonstrated for the first time. Important role of species from Laridae family in unprecedented spreading of H5N1 influenza virus started in 2005 is discussed
Show more [+] Less [-]AGROVOC Keywords
Bibliographic information
This bibliographic record has been provided by Central Scientific Agricultural Library