The efficacy of antihistamine fexofenadine versus methylprednisolone in the treatment of atopic dermatitis in dogs
2009
Plevnik, A., Ljubljana Univ. (Slovenia). Veterinary Fac. | Kobal, S. | Domanjko-Petric, A. | Kotnik, T.
The objective of the study was to establish efficacy of antihistamine fexofenadine in atopic dogs. Thirty atopic dogs over the age of 6 months, of different breeds and sex were randomized into two groups with 15 dogs each. The group F received fexofenadine orally; the group M received methylprednisolone for the period of 6 weeks. CADESI and pruritus score were measured three times during the study (at the baseline, after 3 weeks and after 6 weeks of treatment). Statistically significant discrepancies in CADESI score in comparison with baseline were observed in both groups, namely for 3rd (P=0,007 for group M and P=0,019 for group F) and 6th treatment week (P0,001 for group M and P0,001 for group F). Between the groups statistically significant difference in CADESI score for the 6th week of treatment was observed in favour of group F (P
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