Antibacterial activity of extracts of Acacia aroma against methicillin-resistant and methicillin-sensitive Staphylococcus
2010
Mattana, C.M.(Universidad Nacional de San Luis Facultad de Química, Bioquímica y Farmacia Area Microbiologia) | Satorres, S.E.(Universidad Nacional de San Luis Facultad de Química, Bioquímica y Farmacia Area Microbiologia) | Sosa, A.(Universidad Nacional de San Luis Facultad de Química, Bioquímica y Farmacia Area de Farmacognosia) | Fusco, M.(Universidad Nacional de San Luis Facultad de Química, Bioquímica y Farmacia Area de Farmacognosia) | Alcaráz, L.E.(Universidad Nacional de San Luis Facultad de Química, Bioquímica y Farmacia Area Microbiologia)
Antibacterial activity of organic and aqueous extracts of Acacia aroma was evaluated against methicillin-resistant Staphylococcus aureus (MRSA), methicillin sensitive Staphylococcus aureus (MSSA) and methicillin-resistant Staphylococcus epidermidis. Inhibition of bacterial growth was determined using agar diffusion and bioautographic methods. Among all assayed organic extracts only ethanolic and ethyl acetate extracts presented highest activities against all tested Staphylococcus strains with minimal inhibitory concentration (MIC) values ranging from 2.5 to 10 mg/ml and from 2.5 to 5 mg/ml respectively. The aqueous extracts show little antibacterial activity against Staphylococcus strains. The bioautography assay demonstrated well-defined growth inhibition zones against S. aureus in correspondence with flavonoids and saponins. A. aroma would be an interesting topic for further study and possibly for an alternative treatment for skin infections.
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