Conventional and alternative antifungal therapies to oral candidiasis
2010
Anibal, Paula Cristina(Universidade Estadual de Campinas Faculdade de Odontologia de Piracicaba Departamento de Diagnóstico Oral) | Sardi, Janaina de Cássia Orlandi(Universidade Estadual de Campinas Faculdade de Odontologia de Piracicaba Departamento de Diagnóstico Oral) | Peixoto, Iza Teixeira Alves(Universidade Estadual de Campinas Faculdade de Odontologia de Piracicaba Departamento de Diagnóstico Oral) | Moraes, Julianna Joanna de Carvalho(Universidade Estadual de Campinas Faculdade de Odontologia de Piracicaba Departamento de Diagnóstico Oral) | Höfling, José Francisco(Universidade Estadual de Campinas Faculdade de Odontologia de Piracicaba Departamento de Diagnóstico Oral)
Candida-associated denture stomatitis is the most common form of oral candidal infection, with Candida albicans being the principal etiological agent. Candida adheres directly or via an intermediary layer of plaque-forming bacteria to denture acrylic. Despite antifungal therapy to treat denture stomatitis, infection is reestablished soon after the treatment ceases. In addition, many predisposing factors have been identified as important in the development of oral candidiasis, including malnourishment, common endocrine disorders, such as diabetis mellitus, antibacterial drug therapy, corticosteroids, radiotherapy and other immunocompromised conditions, such as acquired immunodeficiency syndrome (AIDS). These often results in increased tolerance to the most commonly used antifungals. So this review suggests new therapies to oral candidiasis.
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