Mechanisms of self-protection and genes coding for antibiotic biosynthesis, particularly, in microorganisms which produce antibiotic inhibitors of protein synthesis
1988
Paik, S.Y. | Yang, H.C. (Korea Univ., Seoul (Korea R.). Coll. of Agriculture) | Masanori, Sugiyama (Univ., Saijo-Cho Higashi-Hiroshima (Japan). Technology, Faculty of Engineering)
Streptomycetes are attractive microorganisms for their production of various secodary metabolites such as antibiotics. Now, the development of gene manipulation in these microorganisms enables the cloning and analysis of the genes coding for antibiotic biosynthesis and resistance to the drug. In this article, we reviewed the studies with respect to the mechanisms of self-protection and cloning of the genes conding for antibiotic biosynthesis, particularly, in microorganisms which produce antibiotic inhibitors of protein synthesis
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