Effects of Rhus verniciflua Stokes (RVS) Extract on Diet-induced Obesity in C57BL/6 mouse
2003
Jeon, W.K. | Kim, J.H. | Lee, H.W. | Ko, B.S. | Kim, H.K. (Korea Institute of Oriental Medicine, Seoul, Republic of Korea)
We investigated th effects of Rhus verniciflua Stokes (RVS) on high fat diet-induced obesity in C57BL/6 that received ad libitum exposure to a high fat diet for 8 weeks. Male C57BL/6 mice weighing 20.1¡¾0.95 g were divided into four groups and the body weight and food intake were weighed for 8 weeks. After the administration of RVS extract, the liver, subcutaneous and retroperitoneal adipose tissue in the mice were weighed and common blood count in whole blood and biochemical parameters in plasma was measured. It was founded that bldy weight increase was significantly suppressed by the oral administration of RVS extract in group with high fat diet. Weight of subcutaneous adipose tissue and concentration of triglyceride in plasma from mice which were administrated RVS extract were lower than obesity control group. These results suggest that RVS extract may effect on inhibition of diet-induced obesity.
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