Quinone Methide Triterpenes from Tripterygium regelii
Lee, B.W.;Seo, W.D.;Yang, M.S.;Park, K.H.(Gyeongsang National University, Jinju, Republic of Korea)E-mail:khpark@gshp.gsnu.ac.kr | Gal, S.W.(Jinju National University, Jinju, Republic of Korea)
Chloroform extracts of Tripterygium regelii dried root bark afforded three cytotoxic quinone methides, which were identified as pristimerine (1), celastrol (2), and 22β-hydroxy tingenone (3) on the basis of chemical and spectroscopic studies. Compounds 1-3 showed significant cytotoxic (IC∧50 0.20-0.40 ㎍ㆍ㎖-¹) against A549 and SK-OV3 human cancer cell lines, and antibacterial activities against Gram-positive bacteria. 1 was isolated from this plant for the first time.
Show more [+] Less [-]AGROVOC Keywords
Bibliographic information
This bibliographic record has been provided by Korea Agricultural Science Digital Library
