Effects of KH204 on the Relaxation Response of Rabbit Corpus Cavernosum and Reproductive Function in Male Rats
2006
Lee, H.J. (Korea Medical Science Institute, Incheon, Republic of Korea) | Lee, E.J. (Korea Medical Science Institute, Incheon, Republic of Korea) | Kim, H.S. (Korea Medical Science Institute, Incheon, Republic of Korea) | Kim, S.N. (Korea Medical Science Institute, Incheon, Republic of Korea) | Hwang, S.Y. (Korea Medical Science Institute, Incheon, Republic of Korea), E-mail: [email protected]
This study was designed to investigate the effects of KH204 on the relaxation response and reproductive function in male. Strips of rabbit corpus cavernosum were prepared for mounting and isometric tension measurement in an organ bath. On cavernosal strips contracted with 1×10∨-6 phenylephrine and KH204 was applied in increasing concentrations from 0, 61, 183 and 549 mg/L, causing dose-dependent relaxation. Male Sprague-Dawley rats were orally administered with 61, 183 and 549 mg/kg/day of KH204 for 10 weeks.
Show more [+] Less [-]AGROVOC Keywords
Bibliographic information
This bibliographic record has been provided by Korea Agricultural Science Digital Library