Screening of Anti-acne Acitivity of Natural Products against Propionibacterium acnes
2006
Sohn, H.Y. (Andong National University, Andong, Republic of Korea), E-mail: hysohn@andong.ac.kr | Kim, Y.S. (Andong National University, Andong, Republic of Korea) | Kum, E.J. (Andong National University, Andong, Republic of Korea) | Kwon, Y.S. (Andong National University, Andong, Republic of Korea) | Son, K.H. (Andong National University, Andong, Republic of Korea)
Acne is a chronic inflammatory follicular disorder of the skin, occurring in specialized pilosebaceous units on the face, and Propionibacterium acnes, a strict anaerobic pathogen, plays an important role in the pathogenesis of acne. To develop a reliable and effective antiacne agent, we have evaluated antibacterial activity of 500 plant extracts, prepared from 335 plants, against P. acnes. Based on the results of disc-paper method, 25 plant extracts, including the extracts of Chloranthus japonicus (aerial part), Sophora flavescens (radix), Evodia officinalis (fructus), Ginko biloba (semem), Morus alba (root bark), Aralia continentalis (whole) and Reynoutria elliptica (radix), were selected as possible sources of anti-acne agent.
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