In vitro neuronal and osteogenic differentiation of mesenchymal stem cells from human umbilical cord blood
2006
Park, K.S. (Seoul National University, Seoul, Republic of Korea) | Lee, Y.S. (Seoul National University, Seoul, Republic of Korea), E-mail: leeys@snu.ac.kr | Kang, K.S. (Seoul National University, Seoul, Republic of Korea), E-mail: kangpub@snu.ac.kr
Mesenchymal stem cells (MSCs) have the capabilities for self-renewal and differentiation into cells with the phenotypes of bone, cartilage, neurons and fat cells. These features of MSCs have attracted the attention of investigators for using MSCs for cell-based therapies to treat several human diseases. Because bone marrow-derived cells, which are a main source of MSCs, are not always acceptable due to a significant drop in their cell number and proliferative/differentiation capacity with age, human umbilical cord blood (UCB) cells are good substitutes for BMCs due to the immaturity of newborn cells.
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