Standardization of Morinda officinalis How
2006
Lee, H.W. (Korea Institute of Oriental Medicine, Daejeon, Republic of Korea) | Park, S.Y. (Korea Institute of Oriental Medicine, Daejeon, Republic of Korea) | Choo, B.K. (Korea Institute of Oriental Medicine, Daejeon, Republic of Korea) | Chun, J.M. (Korea Institute of Oriental Medicine, Daejeon, Republic of Korea) | Lee, A.Y. (Korea Institute of Oriental Medicine, Daejeon, Republic of Korea) | Kim, H.K. (Korea Institute of Oriental Medicine, Daejeon, Republic of Korea), E-mail: [email protected]
Morinda officinalis How. (Rubiaceae) has been used as tonic, warming, sex impulse and anti-inflammatory agents. Two known anthraquinones, rubiadin-1-methyl ether (Ⅰ) and rubiadin (Ⅱ) were isolated from root of M. officinalis. Their structures were identified using NMR and literature comparisons. The contents of Ⅰ in eighteen M. officinalis were evaluated by HPLC-PDA. Chromatography was performed using a reversed-phase system with Luna C∧18 (2) column and acetonitrile-water (50:50, v/v) with a flow rate of 1.0 mL/min under UV 280 nm. Under these conditions, the content of rubiadin-1-methyl ether was 0.013%.
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