Spaciotemporal Plasticity of Intergeniculate Leaflet Using Genetically Modified Pseudorabies Virus Recombinant
2006
Kim, J.S. (Daegu University, Daegu, Republic of Korea), E-mail: [email protected] | Park, E.S. (Daegu University, Daegu, Republic of Korea) | Cheon, S.H. (Daegu University, Daegu, Republic of Korea) | Kim, M.H. (Daegu University, Daegu, Republic of Korea) | Bang, H.S. (Daegu University, Daegu, Republic of Korea) | Kwon, Y.S. (Daegu University, Daegu, Republic of Korea) | Lee, B.H. (Cheju National University, Jeju, Republic of Korea) | Kim, Y.C. (Keimyung University, Daegu, Republic of Korea)
This study was carried out to investigate the spaciotemporal plasticity of intergeniculate leaflet in postnatal mongolian gerbil using genetically modified pseudorabies virus recombinant, which was a kind of excellent neurotracer with the ability to transpass the neuronal synaptic cleft. In addition, we tried to evaluate the special role of intergeniculate leaflet as a signal controler of circardian rhythm by expression of various neurotransmitters in suprachiasmatic nucleus. The PRV-BaBlu, a genetically modified strain of PRV-Bartha with lac-Z gene, was injected into vitreous body of postnatal mongolian gerbil, and immunostained.
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