Toxicologic Effects of BPA and DEHP on Semen Characteristics in Pig
2006
Park, D.H. (Kangwon National University, Chuncheon, Republic of Korea) | Jang, H.Y. (Kangwon National University, Chuncheon, Republic of Korea) | Cheong, H.T. (Kangwon National University, Chuncheon, Republic of Korea) | Kim, J.T. (Kangwon National University, Chuncheon, Republic of Korea) | Park, C.K. (Kangwon National University, Chuncheon, Republic of Korea) | Kim, C.I. (Kangwon National University, Chuncheon, Republic of Korea) | Yang, B.K. (Kangwon National University, Chuncheon, Republic of Korea), E-mail: [email protected]
The objective of this study was to investigate the toxic effects of Bisphenol A(BPA) and di-2 ethyhexyl phthalate (DEHP) as endocrine disrupters on sperm motility, viability, membrane integrity and abnormality during in vitro incubation of boar semen. Semen were randomly divide into 24 groups and healed with different concentrations of BPA and DEHP (1~100 μM) for 3, 6 and 9 hrs, respectively. The percentages of sperm motility and viability decreased by treatment time with both BPA and DEHP, and obiously differ from the controls.
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