Anti-inflammatory Effect of Aloe Vera and Aloe Arborescens in Phosphatidic Acid-stimulated Raw Cells
2006
Cho, Y.J. (Sangju National University, Sangju, Republic of Korea), E-mail: yjcho@sangju.ac.kr | An, B.J. (Daegu Haany University, Gyeongsan, Republic of Korea) | Kim, M.U. (Kimjeongmoonaloe Co. Ltd., Cheonan, Republic of Korea) | Shim, C.S. (Kimjeongmoonaloe Co. Ltd., Cheonan, Republic of Korea)
With extracted Aloe vera and Aloe arborescens, anti-inflammatory effect was examined in phosphatidic acid-stimulated Raw 264.7 cells. Phosphatidic acid (50 ㎍/ml) treatment increased inflammation related 264.7 cells. The extracts of 80 ㎍/ml concentration from Aloe arborescens reduced the expression of iNOS. Aloe vera and Aloe arborescens also reduced the expression of COX-2, it seems that anti-inflammatory effects of Aloe extracts is partly due to the inhibition of COX-2 expression by inhibiting in Raw 264.7 cells.
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