A Synaptic Model for Pain: Long-Term Potentiation in the Anterior Cingulate Cortex

Zhuo, Min , E-mail: min.zhuo@utoronto.ca

A Synaptic Model for Pain: Long-Term Potentiation in the Anterior Cingulate Cortex

2007

Zhuo, Min (University of Toronto, Toronto, Canada), E-mail: min.zhuo@utoronto.ca

Investigation of molecular and cellular mechanisms of synaptic plasticity is the major focus of many neuroscientists. There are two major reasons for searching new genes and molecules contributing to central plasticity: first, it provides basic neural mechanism for learning and memory, a key function of the brain; second, it provides new targets for treating brain-related disease. Long-term potentiation (LTP), mostly intensely studies in the hippocampus and amygdala, is proposed to be a cellular model for learning and memory.

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AGROVOC Keywords

mice souris

Bibliographic information

Published in

Molecules and Cells

Volume 23 Issue 3 ISSN 1016-8478

Pagination

pp. 259-271

Other Subjects

Persistent pain; Raton; Synaptic plasticity; Immediate early genes; Anterior cingulate cortex; Long-term potentiation; Long-term depression; Adenylyl cyclases; Gene knockout; Fear memory

Language

English

Note

Summary(En)

3 tables

6ill., 78 ref.

Type

Lit. Review

In AGRIS since: 2008-05-15

Format: AGRIS AP

Data Provider

This bibliographic record has been provided by Korea Agricultural Science Digital Library