Anti-atherogenic Effect of Isoflavone through Hypolipidemic, Anti-oxidative and Anti-inflammatory Actions in C57BL/6 Mice
2007
Cho, H.Y. (Paik Inje Memorial Clinical Research Institute, School of Medicine, Inje University, Busan, Republic of Korea) | Yang, J.L. (Busan Regional Korea Food and Drug Administration, Busan, Republic of Korea) | Noh, K.H. (Inje University, Gimhae, Republic of Korea) | Kim, J.J. (Inje University, Gimhae, Republic of Korea) | Kim, Y.H. (Inje University, Gimhae, Republic of Korea) | Huh, K.H. (Inje University, Gimhae, Republic of Korea) | Song, Y.S. (Inje University, Gimhae, Republic of Korea), E-mail: fdsnsong@inje.ac.kr
This study was carried out to investigate the effect of isoflavone on the atherogenic effect in C57BL/6 mice. C57BL/6 female mice, 5 weeks of age, were fed on chow diets for 2 weeks during adjustment period. Mice weighing approximately 17.9±0.9 g were divided into 4 groups and were fed on the experimental diets containing isoflavone for 8 weeks. Experimental groups were control (atherogenic diet), IF-10 (atherogenic diet with isoflavone 10 mg/100 g diet), IF-40 (atherogenic diet with isoflavone 40 mg/100 g diet) and IF-100 (atherogenic diet with isoflavone 100 mg/100 g diet).
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