Phytochemical and Biological Studies on Verbascum sinaiticum Growing in Egypt
2007
Mahmoud, Samia M. (National Research Centre, Dokki, Egypt) | Abdel-Azim, Nahla S. (National Research Centre, Dokki, Egypt) | Shahat, Abdelaaty A. (National Research Centre, Dokki, Egypt), E-mail: aashahat@hotmail.com | Ismail, Shams I. (National Research Centre, Dokki, Egypt) | Hammouda, Faiza M. (National Research Centre, Dokki, Egypt)
The aerial parts of Verbascum sinaiticum Benth. (Scrophulariaceae) yielded two iridoids that were idenified as ajugol 3 and aucubin 4. Also, investigation of the flavonoid constituents revealed the isolation and identification of luteolin 1 and chrysoeriol-7-glucoside 2. All the isolated compounds were identifid by spectroscopicmethods (UV, MS, ¹H-NMR and ∨13C-NMR) and in comparison with the literature data. Both alcohol and methylene chloride/methanol extracts (1 : 1) exhibited a hepatoprotective effect by CCl₄ challenge test.
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