The Search of Pig Pheromonal Odorants for Biostimulation Control System Technologies: Synthesis of N¹-allyl-N²-(tetrahydrofuran-2-ylmethyl)oxalamide Molecule and Induction Effect of Pig Estrus
2009
Park, C.S. (Chungnam National University, Daejeon, Republic of Korea) | Song, S.O. (Chungnam Livestock Technology Research Institute, Cheongyang, Republic of Korea) | Lim, J.S. (Chungnam Livestock Technology Research Institute, Cheongyang, Republic of Korea) | Soung, M.G. (Chungnam National University, Daejeon, Republic of Korea) | Sung, N.D. (Chungnam National University, Daejeon, Republic of Korea), E-mail: [email protected]
To search a new pig pheromonal odorant, the N¹-allyl-N²-(tetrahydrofuran-Z-ylmethyl)oxalamide molecule predicted by ligand based approach and molecular docking method was synthesized by nucleophilic addition-elimination reaction (Ad∧NU-E) between N-allyloxalamic acid ethylester and tetrahydrofurlmethylamine. According to the evaluation results for efficiency of pig estrus control, the synthesized pig pheromonal N¹-allyl-N²-(tetrahydrofuran-2-ylmethyl)oxalamide molecule advanced the estrus by 11.3 days (p less than 0.05) compared with the non-pheromone group. And from these results, it is predicted that the synthesized pig pheromonal compound will be able to increase the reproduction efficiency of pig.
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