Secondary Metabolites of Volvariella bombycina and Their Inhibitory Effects on Melanogenesis
2010
Xu, Guang-Hua, Korea Research Institute of Bioscience and Biotechnology, Daejeon, Republic of Korea | Choo, S.J., Korea Research Institute of Bioscience and Biotechnology, Daejeon, Republic of Korea | Kim, Y.H., Korea Research Institute of Bioscience and Biotechnology, Daejeon, Republic of Korea | Ryoo, I.J., Korea Research Institute of Bioscience and Biotechnology, Daejeon, Republic of Korea | Seok, S.J., National Institute of Agricultural Science and Technology, RDA, Suwon, Republic of Korea | Ahn, J.S., Korea Research Institute of Bioscience and Biotechnology, Daejeon, Republic of Korea | Yoo, I.D., Korea Research Institute of Bioscience and Biotechnology, Daejeon, Republic of Korea
Four compounds were isolated from the culture broth of Volvariella bombycina and they were identified as ergosta-4,6,8(14),22-tetraene-3-one (1), ergosterol peroxide (2), indole-3-carboxaldehyde (3), and indazole (4) by interpretation of spectroscopic data. Among them, compound 2 exhibited melanogenesis inhibitory effect in cultured B16 mouse melanoma cells.
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