Safety Assessment of Oriental Medicines and Their Preparations
2010
Jeong, I.H., Gyeonggi-do Institute of Health and Environment, Suwon, Republic of Korea | Kim, J.H., Gyeonggi-do Institute of Health and Environment, Suwon, Republic of Korea | Jeon, J.S., Gyeonggi-do Institute of Health and Environment, Suwon, Republic of Korea | Cho, S.H., Gyeonggi-do Institute of Health and Environment, Suwon, Republic of Korea | Park, S.H., Gyeonggi-do Institute of Health and Environment, Suwon, Republic of Korea | Jo, H.Y., Gyeonggi-do Institute of Health and Environment, Suwon, Republic of Korea | Kim, Y.S., Gyeonggi-do Institute of Health and Environment, Suwon, Republic of Korea
This study was carried out to evaluate the safety of circulated oriental medicines and their related preparations in Gyeonggi-do. Total 366 samples (165 species) were analyzed about heavy metals, residual contents of sulfur dioxide (SO₂), and 68 samples were analyzed about preservatives. 17 samples (13 species, 4.6%) were exceeded the legal limit of heavy metal. The concentrations over the legal limit for Pb, Cd, As and Hg were 6.1~19.2 mg/kg, 0.4~0.7 mg/kg, 6.9 mg/kg and 0.7 mg/kg, respectively. In particular, the exceeding ratio (5.9%) of the legal limit of heavy metals in foreign products was 3.3 times more than domestic products (1.8%). 13 samples (10 species, 3.6%) exceeded the limit of residual sulfur dioxide and the concentration ranges were 105 to 428 mg/kg in domestic products, on the other hand foreign products were from 114 to 2,468 mg/kg. The mean concentration over the limit of residual sulfur dioxide of foreign products (804 mg/kg) was 2.4 times more than domestic products (338 mg/kg). In studying of the preservatives in oriental preparation, the contents of dehydroacetic acid (48.9~64.1%) in 3 samples of labeled solutions were under the labeled preservative contents and the contents of benzoic acid (139.9%) in 1 sample of labeled pill product was exceeded the labeled preservative contents. The numbers of the detected preservatives in unlabeled solutions, pills and granules were 4, 11 and 7, respectively.
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